Living EuroGuiDerm Guideline for the systemic treatment of psoriasis vulgaris

 

The general recommendations developed in this guideline are based on the Living Cochrane review (https://pubmed.ncbi.nlm.nih.gov/35603936/). With new evidence and new results becoming available, the guideline development group will consider these and decide if and when an update is necessary. This will also be the case for the recommendations for specific clinical and comorbid situations.

 

 

Download entire guideline document in the latest version (September 2023, partial update February 2025): 

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10358

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Introduction, scoping, population and targeted users
09/2023
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650
Disease severity and treatment goals
09/2023
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1215
Methods and evidence section
02/2025
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325
Main Recommendations and Decision Grid
02/2025
Pregnancy changes were added
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1707
Implementation slides
02/2025
New data added
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636
IFPA Guideline
09/2023
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653

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Acitretin
03/2023
No changes, minor editorial changes in 2025
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513
Ciclosporin
03/2023
Reference added
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438
Fumarates
03/2023
No changes
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189
Methotrexate
03/2023
New data added, pregnancy changes were added in 2025
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750
Adalimumab
03/2023
No changes, minor editorial changes in 2025
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354
Apremilast
03/2023
New data added
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421
Bimekizumab
09/2023
New data added
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328
Brodalumab
09/2023
New data added
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133
Certolizumab – Pegol
09/2023
No changes, minor editorial changes in 2025
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147
Deucravacitinib
02/2025
Recommendation concerning laboratory controls updated
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347
Etanercept
03/2023
No changes
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105
Guselkumab
03/2023
No changes
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279
Infliximab
03/2023
No changes, minor editorial changes in 2025
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137
Ixekizumab
09/2023
New data added
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218
Risankizumab
09/2023
New data added
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384
Secukinumab
09/2023
New data added
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241
Tildrakizumab
03/2023
No changes
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180
Ustekinumab
03/2023
No changes
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186
Biosimilars
09/2023
New data added, minor changes in 2025
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150
Newly approved medications and treatments in the pipeline
10/2021
No changes
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301

Last updated
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Psoriatic arthritis
03/2023
New data added, recommendations changed
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555
Inflammatory bowel disease
10/2021
Recommendation concerning bimekizumab added
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224
Cancer
09/2023
New data added, minor changes in 2025
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642
Depression
09/2023
New data added, minor editorial changes in 2025
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163
Diabetes Mellitus
09/2023
New data added, recommendations changed, minor changes in 2025
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252
Heart disease
03/2023
New data added, minor editorial changes in 2025
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302
Kidney disease
03/2023
New data added
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152
Neurological diseases
09/2023
New data added, minor editorial changes in 2025
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178
Viral Hepatitis
02/2025
New data added, recommendations changed
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276
Tuberculosis: Screening
09/2023
Editorial changes, minor editorial changes in 2025
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258
Tuberculosis: Treatment
09/2023
Editorial changes, minor editorial changes in 2025
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268
Wish for child / Pregnancy
02/2025
New data added, recommendations changed
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494
Vaccinations
03/2023
Completely new written
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327
Inmunogenicity
10/2021
No changes
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133

Last updated
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Methods Report
02/2025
Editorial changes
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257
Strength and limitations
09/2023
No changes
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85
Abbreviations
09/2023
Editorial changes
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42