Living EuroGuiDerm Guideline for the systemic treatment of Atopic Eczema

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Last updated
Updated 2025
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Introduction, scoping, population and targeted users
06/2022
Original version
Treatment and treatment goals definitions
06/2022
Original version
Methods Section
03/2025
New information on update
Treatment algorithm (adults + children/adolescents)
02/2025
Lebrikizumab added; approval extension for baricitinib and abrocitinib added to the plan for children/adolescents
Overview tables
03/2025
Lebrikizumab dose, baricitinib children/adolescents dose and abrocitinib adolescents dose added
Implementation slidekit
03/2025
Slides with updated and new recommendations, updated treatment algorithms and updated overview tables

Last updated
Updated 2025
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Basic emollients and moisturizers
06/2022
Original version
Antiinflammatory treatment
06/2022
Original version
Antimicrobial treatment
06/2022
Original version

Last updated
Updated 2025
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Antipruritic treatment
06/2022
Original version

Last updated
Updated 2025
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Phototherapy and photochemotherapy
06/2022
Original version

Last updated
Updated 2025
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Introduction to systemic treatment
03/2025
Minor adjustments to the background text
Azathioprine
02/2025
Minor adjustments to the background text
Ciclosporin
02/2025
Minor adjustments to the background text
Systemic glucocorticosteroids
02/2025
Minor adjustments to the background text
Methotrexate
03/2025
Minor adjustments to the background text
Mycophenolate mofetil
02/2025
Minor adjustments to the background text
Dupilumab
02/2025
Minor adjustments to the background text
Lebrikizumab
02/2025
New recommendation and updated background text
Nemolizumab
02/2025
Updated background text
Omalizumab
10/2022
Updated recommendation
Tralokinumab
03/2025
Minor adjustments to the background text
JAK-Inhibitors introduction
03/2025
Minor adjustments to the background text
Abrocitinib
02/2025
Updated background text
Baricitinib
03/2025
Updated background text
Upadacitinib
03/2025
Minor adjustments to the background text
Other systemic treatment
10/2022
Updated recommendation
Therapies that were used in past
06/2022
Original version

Last updated
Updated 2025
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Patient's perspective
06/2022
Original version
Avoidance techniques in atopic eczema
06/2022
Original version
Dietary interventions in atopic eczema
06/2022
Original version
Allergen-specific immunotherapy
06/2022
Original version
Complementary medicine
06/2022
Original version
Psychological and educational interventions
06/2022
Original version
Occupational aspects
06/2022
Original version

Last updated
Updated 2025
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Pregnancy, breastfeeding, wish for child
03/2025
Updated recommendations and background text
Considerations for paediatric and adolescent patients
06/2022
Original version

Last updated
Updated 2025
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Strengths and limitations
06/2022
Original version
Methods Report
03/2025
New information on update
Evidence Report
09/2024
Updated evidence
Guideline
Previous guideline 2018

Last updated
Updated 2025
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Appendix: Antimicrobial treatment
10/2022
Original version
Appendix: Phototherapy and Photochemotherapy
10/2022
Original version